Thaum pib xyoo 2025, cov kws tshawb fawb los ntawm University of Washington thiab Brigham thiab Women's Hospital (lub tsev kho mob qhia ntawv ntawm Harvard Medical School) tau tshaj tawm ib txoj kev kho mob Alzheimer's - kev ua paxenonroj, uas tsis yog tsuas yog inhibits neuroinflammation thiab txo cov hlwb atrophy, tab sis kuj ua rau cov neuronal tiv thaiv ntau ntxiv.

Xenonthiab Kev Tiv Thaiv Kab Mob Hlwb

Kab mob Alzheimer yog kab mob neurodegenerative feem ntau tshwm sim rau tib neeg, thiab nws qhov ua rau ntseeg tias muaj feem cuam tshuam nrog kev sib sau ua ke ntawm cov protein tau thiab beta-amyloid hauv lub hlwb. Txawm hais tias muaj cov tshuaj uas sim tshem tawm cov protein lom no, lawv tsis tau ua haujlwm zoo hauv kev qeeb qeeb ntawm kev loj hlob ntawm tus kab mob. Yog li ntawd, tsis yog qhov ua rau muaj kab mob lossis kev kho mob tag nrho.

Cov kev tshawb fawb tau qhia tias kev nqus paxenontuaj yeem hla cov ntshav-lub hlwb thaiv thiab txhim kho qhov xwm txheej ntawm cov nas uas muaj tus kab mob Alzheimer's nyob rau hauv chav kuaj mob.Cov kev sim tau muab faib ua ob pawg, ib pawg nas tau pom tias muaj tau protein ntau thiab lwm pawg muaj beta-amyloid protein ntau. Cov txiaj ntsig ntawm kev sim qhia tau tias xenon tsis yog ua rau cov nas ua haujlwm ntau dua xwb, tab sis kuj txhawb nqa kev tiv thaiv ntawm microglia, uas yog qhov tseem ceeb rau kev tshem tawm tau thiab beta-amyloid proteins.

Qhov kev tshawb pom tshiab no yog qhov tshiab heev, qhia tau hais tias cov teebmeem tiv thaiv lub hlwb tuaj yeem tsim tau los ntawm kev ua pa roj inert. Ib qho kev txwv loj hauv kev tshawb fawb thiab kev kho mob Alzheimer's yog tias nws nyuaj heev rau kev tsim cov tshuaj uas tuaj yeem hla cov ntshav-lub hlwb thaiv, thiabxenonua tau qhov no.

Lwm cov ntawv thov kho mob ntawm xenon

1. Tshuaj loog thiab tshuaj loog: Ua ib qho roj zoo tagnrho rau kev siv tshuaj loog,xenonsiv dav vim nws txoj kev pib sai thiab rov zoo, kev ruaj khov ntawm lub plawv thiab cov hlab ntsha thiab kev pheej hmoo tsawg ntawm cov kev mob tshwm sim;

2. Cov nyhuv tiv thaiv hlwb: Ntxiv rau qhov muaj peev xwm kho tau tus kab mob Alzheimer uas tau hais los saum toj no, xenon kuj tau raug kawm los txo qhov kev puas tsuaj rau lub hlwb los ntawm cov menyuam mos uas muaj mob hypoxic-ischemic encephalopathy (HIE);

3. Kev hloov cev thiab kev tiv thaiv:Xenontej zaum yuav pab tiv thaiv cov kab mob pub dawb los ntawm kev raug mob ischemia-reperfusion, uas yog qhov tseem ceeb heev rau kev txhim kho qhov kev vam meej ntawm kev hloov pauv;

4. Kev ua kom mob qog noj ntshav: Qee qhov kev tshawb fawb ua ntej tau qhia tias xenon yuav ua rau cov qog noj ntshav muaj kev rhiab heev rau kev kho mob qog noj ntshav, uas muab txoj hauv kev tshiab rau kev kho mob qog noj ntshav;